ZNF83

Across TCGA patient cohorts, ZNF83 mutation is significantly associated with the RNA expression of many other genes, with 1,607 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF83-associated genes across cancer lineages are CYCSP26, RNU6-728P, and MIR4418. Each is linked with ZNF83 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF83-to-partner and partner-to-ZNF83 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CYCSP26 grouped by ZNF83-low versus ZNF83-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF83→partner) and Y-score (partner→ZNF83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CYCSP26 →	+0.086	+2.162	.002	.006	3	4
HNSC	RNU6-728P →	+0.221	+5.351	<.001	.002	3	3
COAD	MIR4418 →	+0.588	+4.156	<.001	.001	3	3
LUSC	MIR8082 →	+0.707	+6.578	<.001	.001	3	3
HNSC	RNU6-766P →	+0.276	+3.916	.001	.006	3	2
HNSC	RNU6-552P →	+0.307	+5.806	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,607 associations by consensus.

CYCSP26 by ZNF83 expression — UCEC

Explore this box plot interactively →