ZNF827

Across TCGA cell cohorts, ZNF827 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,908 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF827-associated GO terms across cancer lineages are Regulation of cellular response to transforming growth factor beta stimulus, Regulation of G1/S transition of mitotic cell cycle, and Heterochromatin organization. Each is linked with ZNF827 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZNF827-to-partner and partner-to-ZNF827 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cellular response to transforming growth factor beta stimulus grouped by ZNF827-low versus ZNF827-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF827→partner) and Y-score (partner→ZNF827) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cellular response to transforming growth factor beta stimulus →	+0.098	+1.847	<.001	<.001	3	15
LUNG_SCLC	Regulation of G1/S transition of mitotic cell cycle →	+0.079	+0.866	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Heterochromatin organization →	+0.072	+1.284	<.001	<.001	3	14
SKIN	Endosomal transport →	+0.063	+1.520	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of organelle assembly →	+0.056	+1.304	<.001	<.001	3	14
BLOOD_Lymphoma	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.083	+1.270	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,908 associations by consensus.

Regulation of cellular response to transforming growth factor beta stimulus by ZNF827 expression — BONE

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