ZNF827

Across TCGA cell cohorts, ZNF827 mutation is significantly associated with the RNA expression of many other genes, with 247 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF827-associated genes across cancer lineages are LCE2A, IL25, and OR5AK2. Each is linked with ZNF827 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF827-to-partner and partner-to-ZNF827 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCE2A grouped by ZNF827-low versus ZNF827-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF827→partner) and Y-score (partner→ZNF827) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LCE2A →	+0.053	+4.969	<.001	.003	3	2
SOFT_TISSUE	IL25 →	+0.020	+5.977	<.001	.001	3	1
SOFT_TISSUE	OR5AK2 →	+0.548	+5.369	<.001	.004	3	1
SOFT_TISSUE	TMEM95 →	+0.041	+4.930	<.001	.008	3	1
SOFT_TISSUE	CT47B1 →	+0.020	+5.977	<.001	.001	3	1
BLOOD_Myeloma	MMP26 →	+0.026	+4.807	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 247 associations by consensus.

LCE2A by ZNF827 expression — BLOOD_Leukemia

Explore this box plot interactively →