ZNF821

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF821 protein abundance is significantly associated with the RNA expression of many other genes, with 1,569 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF821-associated genes across cancer lineages are ZNF775, ZC3H7B, and PHEX. Each is linked with ZNF821 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF821-to-partner and partner-to-ZNF821 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF821 versus ZNF775 in LSCC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF821→partner) and Y-score (partner→ZNF821) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCZNF775 →+0.680+0.772.001.00232
BRCAZC3H7B →-0.779-0.700.002.00331
BRCAPHEX →-0.862-0.778.002.00131
BRCAABCC1 →-0.869-0.691.002.00131
BRCANOMO1 →-0.786-0.760.001.00531
BRCASPAG1 →-1.031-0.768.006.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,569 associations by consensus.

ZNF821 vs ZNF775 — LSCC

Per-sample scatter of ZNF821 vs ZNF775 in LSCC (Pearson r = 0.52).

Explore this scatter interactively →

Exploration