ZNF821

Across TCGA patient cohorts, ZNF821 mutation is significantly associated with the RNA expression of many other genes, with 1,413 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF821-associated genes across cancer lineages are BPY2DP, PTCD2P2, and OR4V1P. Each is linked with ZNF821 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF821-to-partner and partner-to-ZNF821 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPY2DP grouped by ZNF821-low versus ZNF821-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF821→partner) and Y-score (partner→ZNF821) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	BPY2DP →	+0.281	+5.824	<.001	.001	3	2
COAD	PTCD2P2 →	+0.160	+4.021	<.001	.006	3	2
SKCM	OR4V1P →	+0.048	+4.624	<.001	.005	3	2
READ	TMEM225 →	+0.114	+5.039	<.001	.008	3	2
READ	MIR4494 →	+0.498	+5.219	<.001	.006	3	2
UCEC	MINAR2 →	+0.226	+3.840	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,413 associations by consensus.

BPY2DP by ZNF821 expression — COAD

Explore this box plot interactively →