ZNF821

Across TCGA cell cohorts, ZNF821 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,363 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF821-associated GO terms across cancer lineages are Regulation of DNA-templated transcription initiation, Regulation of transcription initiation by RNA polymerase II, and Protein polyubiquitination. Each is linked with ZNF821 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZNF821-to-partner and partner-to-ZNF821 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA-templated transcription initiation grouped by ZNF821-low versus ZNF821-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF821→partner) and Y-score (partner→ZNF821) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of DNA-templated transcription initiation →	+0.050	+0.609	<.001	<.001	3	15
SOFT_TISSUE	Regulation of transcription initiation by RNA polymerase II →	+0.061	+0.568	<.001	<.001	3	14
LUNG_SCLC	Protein polyubiquitination →	+0.048	+0.986	<.001	.001	3	14
KIDNEY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.111	+0.988	<.001	.001	3	13
BREAST	Regulation of syncytium formation by plasma membrane fusion →	+0.100	+0.960	<.001	.007	3	13
KIDNEY	Golgi vesicle transport →	+0.063	+1.060	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,363 associations by consensus.

Regulation of DNA-templated transcription initiation by ZNF821 expression — OVARY

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