ZNF821

Across TCGA cell cohorts, ZNF821 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF821-associated genes across cancer lineages are OR13G1, ASB17, and C12orf40. Each is linked with ZNF821 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF821-to-partner and partner-to-ZNF821 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13G1 grouped by ZNF821-low versus ZNF821-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF821→partner) and Y-score (partner→ZNF821) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR13G1 →	+0.032	+5.415	<.001	.004	3	1
OVARY	ASB17 →	+0.017	+4.807	<.001	.003	3	1
OVARY	C12orf40 →	+0.011	+4.029	<.001	.009	3	1
BLOOD_Leukemia	LGI1 →	+0.129	+5.539	<.001	.003	3	1
BLOOD_Leukemia	C20orf85 →	+0.049	+5.969	<.001	.001	3	1
BLOOD_Leukemia	IL22 →	+0.050	+6.569	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

OR13G1 by ZNF821 expression — LARGE_INTESTINE

Explore this box plot interactively →