ZNF816

Across TCGA cell cohorts, ZNF816 mutation is significantly associated with the RNA expression of many other genes, with 293 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF816-associated genes across cancer lineages are REG3G, IDI2, and GRM5. Each is linked with ZNF816 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF816-to-partner and partner-to-ZNF816 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REG3G grouped by ZNF816-low versus ZNF816-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF816→partner) and Y-score (partner→ZNF816) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	REG3G →	+0.045	+3.906	.001	.009	3	1
BLOOD_Myeloma	IDI2 →	+0.029	+3.906	.001	.009	3	1
BLOOD_Myeloma	GRM5 →	+0.135	+3.906	.006	.009	3	1
BLOOD_Myeloma	DIPK1C →	+0.015	+3.906	.004	.009	3	1
BLOOD_Myeloma	PRR23A →	+0.060	+4.285	<.001	.003	3	1
BLOOD_Myeloma	C8B →	+0.059	+4.285	.007	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 293 associations by consensus.

REG3G by ZNF816 expression — BLOOD_Myeloma

Explore this box plot interactively →