ZNF815P

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF815P mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF815P-associated genes across cancer lineages are Ku80, PCNA, and PDCD4. Each is linked with ZNF815P in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF815P-to-partner and partner-to-ZNF815P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by ZNF815P-low versus ZNF815P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF815P→partner) and Y-score (partner→ZNF815P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECKu80 →+0.455+3.183<.001.01031
UCECPCNA →+0.244+3.169.039.02031
UCECPDCD4 →-0.768-3.169.002.02031
UCECTuberin →+0.529+3.169<.001.02031
UCECp38-MAPK_pT180_Y182 →-0.612-3.156.013.02021
UCECRad50 →-0.379-3.169.004.02021
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Ku80 by ZNF815P expression — UCEC

Box plot of Ku80 in ZNF815P-low vs ZNF815P-high samples in UCEC.

Explore this box plot interactively →

Exploration