Across TCGA patient cohorts, ZNF814 mutation is significantly associated with the RNA expression of many other genes, with 3,944 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF814-associated genes across cancer lineages are CENPU, SLBP, and SFXN1. Each is linked with ZNF814 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF814-to-partner and partner-to-ZNF814 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF814→partner) and Y-score (partner→ZNF814) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPU →	+0.706	+2.202	<.001	<.001	3	3
UCEC	SLBP →	+0.575	+1.903	<.001	<.001	3	3
COAD	SFXN1 →	+0.611	+3.362	<.001	.004	3	3
COAD	GPHN →	+0.785	+3.335	<.001	.005	3	3
UCEC	TNFRSF10D →	+0.577	+2.415	.004	.003	3	3
UCEC	EXO1 →	+0.591	+2.671	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,944 associations by consensus.

Exploration

ZNF814 survival (RNA) · tumor vs normal (RNA) · all ZNF814 data types