Across TCGA cell cohorts, ZNF814 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF814-associated genes across cancer lineages are TAFA1, LYZL1, and GZMK. Each is linked with ZNF814 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF814-to-partner and partner-to-ZNF814 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF814→partner) and Y-score (partner→ZNF814) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TAFA1 →	+0.206	+3.425	.004	<.001	3	2
LUNG_NSCLC_LUAD	LYZL1 →	+0.020	+4.887	.005	.009	3	2
BREAST	GZMK →	+0.063	+5.169	<.001	.005	3	1
SKIN	ANKRD30BL →	+0.048	+3.684	<.001	.006	3	1
SKIN	HSFY2 →	+0.019	+3.930	<.001	.003	3	1
OVARY	OR10C1 →	+0.005	+4.807	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

ZNF814 survival (RNA) · tumor vs normal (RNA) · all ZNF814 data types