Across TCGA patient cohorts, ZNF81 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,103 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF81-associated proteins across cancer lineages are DIP2C_S89, HUWE1, and TCEAL1. Each is linked with ZNF81 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF81-to-partner and partner-to-ZNF81 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF81→partner) and Y-score (partner→ZNF81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	DIP2C_S89 →	+1.864	+0.521	<.001	<.001	3	5
LUAD	HUWE1 →	+0.280	+0.390	<.001	<.001	3	5
BRCA	TCEAL1 →	+0.439	+0.372	.001	<.001	3	5
BRCA	CLPX →	-0.244	-0.603	<.001	<.001	3	4
COAD	CLUH →	-0.305	-0.293	<.001	.003	3	4
LSCC	CUL4B →	+0.262	+0.343	<.001	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,103 associations by consensus.

Exploration

ZNF81 survival (RNA) · tumor vs normal (RNA) · all ZNF81 data types