Across TCGA patient cohorts, ZNF81 mutation is significantly associated with the RNA expression of many other genes, with 4,033 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF81-associated genes across cancer lineages are IMP4, PITPNA-AS1, and MIR3180-4. Each is linked with ZNF81 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF81-to-partner and partner-to-ZNF81 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF81→partner) and Y-score (partner→ZNF81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IMP4 →	+0.231	+1.348	.003	.003	3	3
UCEC	PITPNA-AS1 →	+0.433	+2.247	.003	.001	3	3
BRCA	MIR3180-4 →	+0.170	+5.365	<.001	.002	3	3
GBM	MIR7975 →	+0.770	+5.857	<.001	.002	3	2
READ	LINC02548 →	+0.137	+5.257	<.001	.002	3	2
READ	MIR4450 →	+0.491	+4.421	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,033 associations by consensus.

Exploration

ZNF81 survival (RNA) · tumor vs normal (RNA) · all ZNF81 data types