Across TCGA cell cohorts, ZNF81 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,330 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF81-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Microtubule nucleation, and Growth hormone secretion. Each is linked with ZNF81 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZNF81-to-partner and partner-to-ZNF81 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF81→partner) and Y-score (partner→ZNF81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of gene expression, epigenetic →	+0.065	+0.722	<.001	<.001	3	15
BONE	Microtubule nucleation →	+0.139	+0.818	<.001	<.001	3	15
URINARY_TRACT	Growth hormone secretion →	+0.104	+0.793	<.001	<.001	3	14
BREAST	Regulation of sister chromatid segregation →	+0.090	+0.771	.009	.001	3	14
SKIN	Cytosolic transport →	+0.072	+0.792	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Heterochromatin formation →	+0.061	+0.639	.001	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,330 associations by consensus.

Exploration

ZNF81 survival (RNA) · tumor vs normal (RNA) · all ZNF81 data types