Across TCGA cell cohorts, ZNF81 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ZNF81-associated genes across cancer lineages are GAGE12D, GAGE12C, and SHOX. Each is linked with ZNF81 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF81-to-partner and partner-to-ZNF81 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF81→partner) and Y-score (partner→ZNF81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	GAGE12D →	+1.186	+6.357	<.001	<.001	3	1
CNS	GAGE12C →	+1.186	+6.357	<.001	<.001	3	1
LARGE_INTESTINE	SHOX →	+0.040	+3.793	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

ZNF81 survival (RNA) · tumor vs normal (RNA) · all ZNF81 data types