ZNF806

Across TCGA pan-cancer cohorts, ZNF806 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZNF806 data layer compared with 15 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher ZNF806 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF806 expression acts as an unfavorable survival marker.

LUSC and HNSC are the cancer types where ZNF806 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	All	0.079	0.792	<.001	36	view →
HNSC	DFS	Median	All	0.170	0.696	.010	18	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ZNF806–LUSC (DFS)

Open the LUSC breakdown →