ZNF805

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ZNF805 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZNF805 data layer compared with 25 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ZNF805 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF805 expression acts as an unfavorable survival marker.

ACC, KIRP, and KICH are the cancer types where ZNF805 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCDFSMedianAll0.0460.753<.00136view →
KIRPOSMedianII,III,IV0.1410.772<.00128view →
KICHDFSMedianAll0.1020.848.00413view →
UCECOSMedianIV0.2310.592.0366view →
READOSMedianAll0.2810.830.0063view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration