Across TCGA patient cohorts, ZNF805 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF805-associated genes across cancer lineages are eEF2, ATM, and Caspase-7-cleavedD198. Each is linked with ZNF805 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF805-to-partner and partner-to-ZNF805 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF805→partner) and Y-score (partner→ZNF805) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.355	+2.000	.008	.030	3	2
UCEC	ATM →	-0.515	-3.571	.002	.002	3	2
UCEC	Caspase-7-cleavedD198 →	+0.727	+3.479	.001	.002	3	2
UCEC	Cyclin-E2 →	+0.218	+2.009	<.001	.017	3	2
UCEC	EGFR_pY1068 →	-0.296	-2.662	.001	<.001	3	1
UCEC	ERK2 →	+0.163	+2.000	.023	.029	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

ZNF805 survival (RNA) · tumor vs normal (RNA) · all ZNF805 data types