Across TCGA cell cohorts, ZNF805 mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF805-associated genes across cancer lineages are ADAM7, F11, and KLF1. Each is linked with ZNF805 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF805-to-partner and partner-to-ZNF805 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF805→partner) and Y-score (partner→ZNF805) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ADAM7 →	+0.004	+3.023	<.001	.002	3	2
LARGE_INTESTINE	F11 →	+0.036	+3.204	<.001	<.001	3	2
LARGE_INTESTINE	KLF1 →	+0.079	+3.215	.006	.009	3	1
LARGE_INTESTINE	PPP2R5D →	+0.852	+3.064	<.001	.009	3	1
LARGE_INTESTINE	SMAD9 →	+1.284	+3.082	<.001	.007	3	1
LARGE_INTESTINE	UBE2G1 →	+0.609	+3.215	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

Exploration

ZNF805 survival (RNA) · tumor vs normal (RNA) · all ZNF805 data types