ZNF804B

Across TCGA patient cohorts, ZNF804B mutation is significantly associated with the total protein of many other genes, with 81 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF804B-associated genes across cancer lineages are PDCD4, Src, and NF2. Each is linked with ZNF804B in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF804B-to-partner and partner-to-ZNF804B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by ZNF804B-low versus ZNF804B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF804B→partner) and Y-score (partner→ZNF804B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.378	-1.678	.004	.019	3	4
COAD	Src →	-0.206	-3.309	.011	.009	3	4
SKCM	NF2 →	+0.208	+1.874	.017	.002	3	4
READ	MIG-6 →	+0.184	+2.903	<.001	.023	3	3
LUSC	4E-BP1_pS65 →	+0.097	+1.298	.023	.027	3	3
LUSC	CDK1 →	+0.081	+1.925	.016	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 81 associations by consensus.

PDCD4 by ZNF804B expression — UCEC

Explore this box plot interactively →