ZNF804B

Across TCGA cell cohorts, ZNF804B mutation is significantly associated with the RNA expression of many other genes, with 868 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF804B-associated genes across cancer lineages are ANKRD31, TTC5, and PRPSAP2. Each is linked with ZNF804B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF804B-to-partner and partner-to-ZNF804B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD31 grouped by ZNF804B-low versus ZNF804B-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF804B→partner) and Y-score (partner→ZNF804B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ANKRD31 →	+0.138	+3.385	.002	.004	3	2
LARGE_INTESTINE	TTC5 →	+0.592	+1.949	.002	.002	3	2
SKIN	PRPSAP2 →	+0.614	+3.299	<.001	.004	3	2
SKIN	FAM86B1 →	+1.130	+3.064	<.001	.009	3	2
SKIN	CT45A2 →	+0.959	+2.353	<.001	.008	3	2
LARGE_INTESTINE	USP14 →	+0.607	+2.672	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 868 associations by consensus.

ANKRD31 by ZNF804B expression — SKIN

Explore this box plot interactively →