ZNF80

Across TCGA patient cohorts, ZNF80 mutation is significantly associated with the RNA expression of many other genes, with 1,502 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF80-associated genes across cancer lineages are MPV17L, KRT8P36, and CRYBB2P1. Each is linked with ZNF80 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF80-to-partner and partner-to-ZNF80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPV17L grouped by ZNF80-low versus ZNF80-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF80→partner) and Y-score (partner→ZNF80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MPV17L →	-0.741	-2.690	.005	.006	3	3
SKCM	KRT8P36 →	+0.166	+3.296	.005	.007	3	2
UCEC	CRYBB2P1 →	+0.524	+3.191	<.001	<.001	3	2
UCEC	BNIP3L →	+0.576	+2.502	.006	.002	3	2
UCEC	MINDY4 →	-0.404	-3.148	.004	<.001	3	2
UCEC	SNX8 →	+0.620	+3.180	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,502 associations by consensus.

MPV17L by ZNF80 expression — SKCM

Explore this box plot interactively →