ZNF80

Across TCGA cell cohorts, ZNF80 RNA expression is significantly associated with the go_rna of many other GO terms, with 783 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF80-associated GO terms across cancer lineages are Regulation of DNA biosynthetic process, Positive regulation of telomere maintenance, and Positive regulation of hematopoietic progenitor cell differentiation. Each is linked with ZNF80 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF80-to-partner and partner-to-ZNF80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA biosynthetic process grouped by ZNF80-low versus ZNF80-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF80→partner) and Y-score (partner→ZNF80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of DNA biosynthetic process →	+0.045	+0.117	<.001	.006	3	5
BLOOD_Leukemia	Positive regulation of telomere maintenance →	+0.046	+0.157	.001	.004	3	5
LUNG_SCLC	Positive regulation of hematopoietic progenitor cell differentiation →	+0.113	+0.064	.009	.003	3	4
BLOOD_Leukemia	Positive regulation of chromosome organization →	+0.041	+0.092	<.001	.001	3	4
BLOOD_Leukemia	Signal transduction in response to DNA damage →	+0.042	+0.126	<.001	.002	3	4
BLOOD_Leukemia	UMP salvage →	+0.127	+0.064	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 783 associations by consensus.

Regulation of DNA biosynthetic process by ZNF80 expression — BLOOD_Leukemia

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