ZNF80

Across TCGA cell cohorts, ZNF80 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF80-associated genes across cancer lineages are G6PC2, FAM205A, and WNT8A. Each is linked with ZNF80 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF80-to-partner and partner-to-ZNF80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, G6PC2 grouped by ZNF80-low versus ZNF80-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF80→partner) and Y-score (partner→ZNF80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	G6PC2 →	+0.032	+3.658	<.001	.005	3	1
LARGE_INTESTINE	FAM205A →	+0.020	+3.614	<.001	.006	3	1
LARGE_INTESTINE	WNT8A →	+0.018	+3.632	.007	.003	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

G6PC2 by ZNF80 expression — LARGE_INTESTINE

Explore this box plot interactively →