ZNF8

Across TCGA patient cohorts, ZNF8 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,930 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF8-associated proteins across cancer lineages are TRIM28, UBE2M, and SAE1. Each is linked with ZNF8 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF8-to-partner and partner-to-ZNF8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF8 versus TRIM28 in LSCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF8→partner) and Y-score (partner→ZNF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRIM28 →	+0.466	+0.689	<.001	<.001	3	8
BRCA	UBE2M →	+0.346	+0.530	<.001	<.001	3	7
GBM	SAE1 →	+0.383	+0.502	<.001	<.001	3	7
HNSC	BRD3_S563 →	+0.491	+0.723	<.001	<.001	3	6
HNSC	MORF4L1 →	+0.294	+0.669	<.001	.001	3	6
GBM	POGZ →	+0.292	+0.611	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,930 associations by consensus.

ZNF8 vs TRIM28 — LSCC

Explore this scatter interactively →