ZNF8

Across TCGA patient cohorts, ZNF8 protein abundance is significantly associated with the RNA expression of many other genes, with 7,710 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF8-associated genes across cancer lineages are SAPCD2, CTSH, and ELL2. Each is linked with ZNF8 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF8-to-partner and partner-to-ZNF8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF8 versus SAPCD2 in GBM, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF8→partner) and Y-score (partner→ZNF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SAPCD2 →	+1.085	+0.433	<.001	<.001	3	4
LUAD	CTSH →	-0.881	-0.236	.005	.007	3	3
OV	ELL2 →	-0.909	-0.472	.001	.001	3	3
GBM	FLVCR2 →	-0.744	-0.539	<.001	<.001	3	3
OV	SQOR →	-0.893	-0.529	.002	.002	3	3
GBM	SLC16A3 →	-0.740	-0.477	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,710 associations by consensus.

ZNF8 vs SAPCD2 — GBM

Explore this scatter interactively →