ZNF8

Across TCGA cell cohorts, ZNF8 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,003 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF8-associated GO terms across cancer lineages are Heterochromatin organization, Epigenetic regulation of gene expression, and Heterochromatin formation. Each is linked with ZNF8 in more than 18 cancer types. Because this analysis shows association rather than direction, both ZNF8-to-partner and partner-to-ZNF8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin organization grouped by ZNF8-low versus ZNF8-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF8→partner) and Y-score (partner→ZNF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Heterochromatin organization →	+0.098	+0.847	<.001	<.001	3	19
STOMACH	Epigenetic regulation of gene expression →	+0.073	+1.087	.003	.001	3	18
OVARY	Heterochromatin formation →	+0.090	+0.576	<.001	.002	3	18
BLOOD_Lymphoma	RNA catabolic process →	+0.065	+0.821	<.001	<.001	3	18
SOFT_TISSUE	Negative regulation of gene expression, epigenetic →	+0.077	+0.864	<.001	<.001	3	17
BLOOD_Lymphoma	mRNA catabolic process →	+0.060	+0.763	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,003 associations by consensus.

Heterochromatin organization by ZNF8 expression — BONE

Explore this box plot interactively →