ZNF792

Across TCGA patient cohorts, ZNF792 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF792-associated genes across cancer lineages are HER2_pY1248, Ku80, and Notch1. Each is linked with ZNF792 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF792-to-partner and partner-to-ZNF792 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HER2_pY1248 grouped by ZNF792-low versus ZNF792-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF792→partner) and Y-score (partner→ZNF792) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HER2_pY1248 →	-0.176	-1.584	.049	.009	3	2
UCEC	Ku80 →	+0.198	+1.598	.012	.006	3	2
UCEC	Notch1 →	+0.106	+1.498	.024	.032	3	2
UCEC	TFRC →	+0.483	+2.459	.006	.018	3	2
UCEC	Caspase-7-cleavedD198 →	+0.971	+3.247	<.001	<.001	3	2
UCEC	EGFR_pY1068 →	-0.237	-2.906	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

HER2_pY1248 by ZNF792 expression — UCEC

Explore this box plot interactively →