ZNF79

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF79 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF79-associated genes across cancer lineages are Caspase-7-cleavedD198, EGFR, and eIF4E. Each is linked with ZNF79 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF79-to-partner and partner-to-ZNF79 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF79→partner) and Y-score (partner→ZNF79) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCaspase-7-cleavedD198 →+1.413+2.906<.001.00132
UCECEGFR →-0.172-1.700.011.04431
UCECeIF4E →+0.213+2.906.017.00131
UCECMEK1 →+0.390+2.222.011.01131
UCECNotch1 →+0.188+1.700.001.04431
UCECp62 Lck ligand →+0.440+2.469.001.01031
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration