Across TCGA patient cohorts, ZNF789 protein abundance is significantly associated with the RNA expression of many other genes, with 1,635 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF789-associated genes across cancer lineages are MAPK1, PRODH, and XBP1. Each is linked with ZNF789 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF789-to-partner and partner-to-ZNF789 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF789→partner) and Y-score (partner→ZNF789) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MAPK1 →	+0.586	+0.534	.007	.003	3	1
GBM	PRODH →	+1.289	+0.555	<.001	.001	3	1
GBM	XBP1 →	-0.669	-0.482	<.001	.001	3	1
GBM	PLEK2 →	-0.581	-0.577	.008	.004	3	1
GBM	NDRG3 →	+0.927	+0.680	<.001	<.001	3	1
GBM	HRH3 →	+1.164	+0.570	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,635 associations by consensus.

Exploration

ZNF789 survival (RNA) · tumor vs normal (RNA) · all ZNF789 data types