Across TCGA patient cohorts, ZNF789 mutation is significantly associated with the RNA expression of many other genes, with 3,515 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF789-associated genes across cancer lineages are RNU4-64P, RNU1-57P, and RNU6-560P. Each is linked with ZNF789 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF789-to-partner and partner-to-ZNF789 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF789→partner) and Y-score (partner→ZNF789) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU4-64P →	+0.291	+6.339	<.001	<.001	3	3
UCEC	RNU1-57P →	+0.121	+3.411	<.001	.002	3	3
HNSC	RNU6-560P →	+0.560	+5.736	<.001	.003	3	2
UCEC	LHX5 →	+0.204	+1.634	.002	.005	3	2
COAD	OR9Q2 →	+0.037	+4.399	<.001	.006	3	2
SKCM	IGLV3-26 →	+0.240	+5.680	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,515 associations by consensus.

Exploration

ZNF789 survival (RNA) · tumor vs normal (RNA) · all ZNF789 data types