ZNF789

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF789 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF789-associated genes across cancer lineages are eEF2, INPP4B, and P-Cadherin. Each is linked with ZNF789 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF789-to-partner and partner-to-ZNF789 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF789→partner) and Y-score (partner→ZNF789) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECeEF2 →+0.323+2.321.010.03332
UCECINPP4B →-0.272-1.999.017.00832
UCECP-Cadherin →-0.125-3.459.014.00532
UCECPCNA →+0.221+2.000.003.00932
UCECShc_pY317 →-0.176-2.222<.001.00932
UCECATM →-0.488-2.906.002.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration