ZNF787

Across TCGA pan-cancer cohorts, ZNF787 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ZNF787 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ZNF787 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF787 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

HNSC, CCRCC, and LUAD are the cancer types where ZNF787 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	IV	0.458	0.791	.002	15	view →
CCRCC	DFS	Quartile	All	0.834	1.000	.010	12	view →
LUAD	OS	Median	III,IV	1.000	0.770	.006	5	view →
GBM	DFS	Quartile	All	0.205	0.543	.026	4	view →
PDAC	OS	Median	III,IV	0.399	0.777	.033	3	view →
LSCC	DFS	Median	All	0.970	0.909	.036	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ZNF787–HNSC (DFS)

Open the HNSC breakdown →