ZNF787

Across TCGA patient cohorts, ZNF787 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF787-associated genes across cancer lineages are EGFR_pY1068, ERK2, and Lck. Each is linked with ZNF787 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF787-to-partner and partner-to-ZNF787 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by ZNF787-low versus ZNF787-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF787→partner) and Y-score (partner→ZNF787) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.291	-2.321	.020	.035	3	1
UCEC	ERK2 →	+0.247	+3.459	.010	.005	3	1
UCEC	Lck →	+0.307	+3.169	.002	.018	3	1
UCEC	MEK1 →	+0.397	+3.000	.030	.036	3	1
UCEC	p27 →	+0.273	+2.321	.012	.035	3	1
UCEC	TIGAR →	+0.233	+2.348	.002	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

EGFR_pY1068 by ZNF787 expression — UCEC

Explore this box plot interactively →