ZNF787

Across TCGA cell cohorts, ZNF787 mutation is significantly associated with the RNA expression of many other genes, with 246 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF787-associated genes across cancer lineages are CYP26B1, LYZL1, and C20orf173. Each is linked with ZNF787 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF787-to-partner and partner-to-ZNF787 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CYP26B1 grouped by ZNF787-low versus ZNF787-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF787→partner) and Y-score (partner→ZNF787) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CYP26B1 →	+1.096	+3.212	.001	.006	3	2
OVARY	LYZL1 →	+0.040	+4.990	<.001	.001	3	1
OVARY	C20orf173 →	+0.031	+4.029	<.001	.009	3	1
BLOOD_Leukemia	GML →	+0.080	+3.567	<.001	.003	3	1
BLOOD_Leukemia	LGI1 →	+0.066	+4.539	<.001	<.001	3	1
BLOOD_Leukemia	MMP27 →	+0.013	+3.969	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 246 associations by consensus.

CYP26B1 by ZNF787 expression — LARGE_INTESTINE

Explore this box plot interactively →