Across TCGA patient cohorts, ZNF786 mutation is significantly associated with the RNA expression of many other genes, with 4,342 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF786-associated genes across cancer lineages are PTMAP4, FGD5, and NAE1. Each is linked with ZNF786 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF786-to-partner and partner-to-ZNF786 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF786→partner) and Y-score (partner→ZNF786) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PTMAP4 →	+0.729	+2.008	.001	.001	3	4
UCEC	FGD5 →	-0.496	-2.742	.002	.003	3	3
UCEC	NAE1 →	+0.520	+2.369	<.001	<.001	3	3
UCEC	GHITM →	+0.495	+2.099	<.001	<.001	3	3
UCEC	LSM3 →	+0.428	+3.949	.001	<.001	3	3
UCEC	IL2RB →	+0.855	+4.010	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,342 associations by consensus.

Exploration

ZNF786 survival (RNA) · tumor vs normal (RNA) · all ZNF786 data types