ZNF786

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF786 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF786-associated genes across cancer lineages are Notch1, p62 Lck ligand, and P-Cadherin. Each is linked with ZNF786 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF786-to-partner and partner-to-ZNF786 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF786→partner) and Y-score (partner→ZNF786) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNotch1 →+0.154+2.183<.001.00132
UCECp62 Lck ligand →+0.398+2.321<.001<.00132
UCECP-Cadherin →-0.109-1.874.019.04932
UCECATM →-0.518-2.321<.001<.00132
SKCMMYH11 →-0.889-2.000.021.03132
UCEC14-3-3_beta →-0.071-2.088.030.01631
Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

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