Across TCGA cell cohorts, ZNF786 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF786-associated genes across cancer lineages are OR52H1, OR5V1, and GJA8. Each is linked with ZNF786 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF786-to-partner and partner-to-ZNF786 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF786→partner) and Y-score (partner→ZNF786) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR52H1 →	+0.032	+3.669	<.001	<.001	3	2
SKIN	OR5V1 →	+0.016	+4.977	<.001	.007	3	2
STOMACH	GJA8 →	+0.015	+4.285	<.001	.007	3	2
SOFT_TISSUE	IFNA8 →	+0.052	+4.930	<.001	.008	3	1
SOFT_TISSUE	SPRR3 →	+0.061	+4.930	<.001	.008	3	1
SOFT_TISSUE	TEX55 →	+0.026	+5.369	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

ZNF786 survival (RNA) · tumor vs normal (RNA) · all ZNF786 data types