Across TCGA patient cohorts, ZNF783 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF783-associated genes across cancer lineages are ACC1, JNK_pT183_Y185, and JNK2. Each is linked with ZNF783 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF783-to-partner and partner-to-ZNF783 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF783→partner) and Y-score (partner→ZNF783) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.414	+3.013	.014	.018	3	1
UCEC	JNK_pT183_Y185 →	-0.223	-3.169	.004	.019	3	1
UCEC	JNK2 →	+0.233	+2.817	.012	.036	3	1
UCEC	MSH2 →	-0.385	-2.973	<.001	.035	3	1
UCEC	p70-S6K →	+0.196	+3.019	.029	.019	3	1
UCEC	PRAS40_pT246 →	+0.254	+3.321	.001	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

ZNF783 survival (RNA) · tumor vs normal (RNA) · all ZNF783 data types