Across TCGA cell cohorts, ZNF783 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF783-associated genes across cancer lineages are PRAMEF15, IQCF6, and TAS2R39. Each is linked with ZNF783 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF783-to-partner and partner-to-ZNF783 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF783→partner) and Y-score (partner→ZNF783) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	PRAMEF15 →	+0.017	+4.614	<.001	.004	3	1
PANCREAS	IQCF6 →	+0.123	+5.139	<.001	<.001	3	1
OESOPHAGUS	TAS2R39 →	+0.043	+4.906	<.001	.006	3	1
BLOOD_Leukemia	GOLGA6L2 →	+0.019	+3.705	<.001	.007	3	1
BLOOD_Leukemia	SLC36A2 →	+0.018	+3.551	<.001	.009	3	1
BLOOD_Leukemia	PRSS41 →	+0.055	+4.060	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

ZNF783 survival (RNA) · tumor vs normal (RNA) · all ZNF783 data types