ZNF782

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF782 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF782-associated genes across cancer lineages are Shc_pY317, EGFR_pY1068, and p38-MAPK_pT180_Y182. Each is linked with ZNF782 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF782-to-partner and partner-to-ZNF782 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF782→partner) and Y-score (partner→ZNF782) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECShc_pY317 →-0.160-1.584.001.00933
UCECEGFR_pY1068 →-0.212-1.906.011.01532
UCECp38-MAPK_pT180_Y182 →-0.355-1.415.018.04332
UCECCaspase-7-cleavedD198 →+0.430+1.697.030.01232
UCECCaspase-8 →-0.256-2.201.002<.00132
UCEC4E-BP1 →+0.354+3.807<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

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