Across TCGA patient cohorts, ZNF781 mutation is significantly associated with the RNA expression of many other genes, with 2,381 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF781-associated genes across cancer lineages are RNU6-880P, MIR668, and RNA5SP158. Each is linked with ZNF781 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF781-to-partner and partner-to-ZNF781 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF781→partner) and Y-score (partner→ZNF781) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-880P →	+0.581	+3.841	.002	.005	3	4
HNSC	MIR668 →	+0.396	+7.954	<.001	.008	3	3
UCEC	RNA5SP158 →	+0.086	+2.840	<.001	.001	3	3
SKCM	H2AC2P →	+0.062	+5.003	<.001	.002	3	3
READ	HIKESHIP1 →	+0.604	+3.781	<.001	.009	3	2
READ	RNU6-893P →	+0.738	+4.860	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,381 associations by consensus.

Exploration

ZNF781 survival (RNA) · tumor vs normal (RNA) · all ZNF781 data types