Across TCGA patient cohorts, ZNF781 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF781-associated genes across cancer lineages are ATM, eIF4E, and TFRC. Each is linked with ZNF781 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF781-to-partner and partner-to-ZNF781 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF781→partner) and Y-score (partner→ZNF781) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.415	-1.664	.002	.019	3	3
UCEC	eIF4E →	+0.162	+1.754	.011	.001	3	2
UCEC	TFRC →	+0.413	+1.125	.010	.033	3	2
UCEC	Caspase-7-cleavedD198 →	+0.396	+1.300	.027	.034	3	2
UCEC	14-3-3_beta →	-0.076	-1.780	.012	.024	3	1
UCEC	EGFR_pY1068 →	-0.221	-1.999	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

ZNF781 survival (RNA) · tumor vs normal (RNA) · all ZNF781 data types