Across TCGA cell cohorts, ZNF781 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,020 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF781-associated GO terms across cancer lineages are RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, mRNA splicing, via spliceosome, and Transcription initiation at RNA polymerase II promoter. Each is linked with ZNF781 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF781-to-partner and partner-to-ZNF781 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF781→partner) and Y-score (partner→ZNF781) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.068	+1.060	<.001	<.001	3	9
CNS	mRNA splicing, via spliceosome →	+0.068	+1.060	<.001	<.001	3	9
BLOOD_Lymphoma	Transcription initiation at RNA polymerase II promoter →	+0.051	+0.565	<.001	.003	2	8
BLOOD_Lymphoma	DNA-templated transcription initiation →	+0.053	+0.507	<.001	.008	2	8
BLOOD_Lymphoma	Negative regulation of adaptive immune response →	-0.068	-0.442	<.001	.002	3	7
SKIN	Regulation of chromosome organization →	+0.051	+0.589	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,020 associations by consensus.

Exploration

ZNF781 survival (RNA) · tumor vs normal (RNA) · all ZNF781 data types