Across TCGA patient cohorts, ZNF780A mutation is significantly associated with the total protein of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF780A-associated genes across cancer lineages are p38-MAPK_pT180_Y182, Cyclin-E2, and Lck. Each is linked with ZNF780A in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF780A-to-partner and partner-to-ZNF780A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF780A→partner) and Y-score (partner→ZNF780A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p38-MAPK_pT180_Y182 →	-0.264	-1.152	.039	.048	3	3
SKCM	Cyclin-E2 →	+0.197	+3.012	.017	.018	3	3
COAD	Lck →	+0.317	+3.025	.045	.019	3	2
UCEC	EGFR_pY1068 →	-0.178	-1.398	.012	.004	3	2
UCEC	p27_pT198 →	+0.076	+1.222	.012	.011	3	2
UCEC	Rad50 →	-0.233	-2.000	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

Exploration

ZNF780A survival (RNA) · tumor vs normal (RNA) · all ZNF780A data types