Across TCGA cell cohorts, ZNF777 mutation is significantly associated with the RNA expression of many other genes, with 634 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF777-associated genes across cancer lineages are OPN1MW, CENPH, and PRIMPOL. Each is linked with ZNF777 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF777-to-partner and partner-to-ZNF777 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF777→partner) and Y-score (partner→ZNF777) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OPN1MW →	+0.087	+3.887	<.001	.002	3	2
BLOOD_Leukemia	CENPH →	+0.788	+3.366	<.001	.002	3	2
LARGE_INTESTINE	PRIMPOL →	+0.705	+3.502	<.001	.001	3	2
BLOOD_Leukemia	CCDC110 →	+0.414	+3.662	.003	.002	3	2
BLOOD_Leukemia	ELMOD2 →	+0.570	+3.489	.003	.001	3	2
BLOOD_Leukemia	SBK1 →	+1.442	+3.214	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 634 associations by consensus.

Exploration

ZNF777 survival (RNA) · tumor vs normal (RNA) · all ZNF777 data types