Across TCGA cell cohorts, ZNF775 mutation is significantly associated with the RNA expression of many other genes, with 688 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF775-associated genes across cancer lineages are PPM1M, PFN2, and TXNDC15. Each is linked with ZNF775 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF775-to-partner and partner-to-ZNF775 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF775→partner) and Y-score (partner→ZNF775) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PPM1M →	+1.123	+3.411	.001	.003	3	2
BLOOD_Leukemia	PFN2 →	+2.548	+3.351	<.001	.003	3	2
LARGE_INTESTINE	TXNDC15 →	+0.757	+3.364	<.001	.002	3	2
LARGE_INTESTINE	GCH1 →	+0.618	+3.364	.003	.002	3	2
LARGE_INTESTINE	PTTG2 →	+0.079	+3.719	<.001	.001	3	2
CNS	H1-8 →	+0.022	+5.357	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 688 associations by consensus.

Exploration

ZNF775 survival (RNA) · tumor vs normal (RNA) · all ZNF775 data types