ZNF775-AS1

Across TCGA pan-cancer cohorts, ZNF775-AS1 RNA is linked to patient survival in 29 of 34 cancer types, making it the most broadly survival-associated ZNF775-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ZNF775-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF775-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

KIRC, HNSC, and COAD are the cancer types where ZNF775-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.499	0.727	<.001	124	view →
HNSC	OS	Median	II,III,IV	0.713	0.583	<.001	124	view →
COAD	DFS	Quartile	All	0.728	0.869	<.001	82	view →
PAAD	OS	Median	All	0.519	0.254	<.001	72	view →
UVM	DFS	Median	III,IV	0.186	0.903	<.001	55	view →
THYM	DFS	Quartile	II,III,IV	0.951	0.468	.001	54	view →
THCA	OS	Quartile	III,IV	0.933	1.000	.002	41	view →
UCS	OS	Tertile	IV	0.844	0.242	.024	40	view →
READ	OS	Tertile	II,III,IV	1.000	0.797	.005	35	view →
CESC	DFS	Median	All	0.779	0.867	.014	28	view →
STAD	OS	Median	IV	0.564	0.192	.004	27	view →
LIHC	DFS	Tertile	All	0.452	0.670	<.001	25	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 29 lineages.

ZNF775-AS1–KIRC (DFS)

Open the KIRC breakdown →