Across TCGA patient cohorts, ZNF774 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,633 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF774-associated proteins across cancer lineages are NAXE, HNRNPR, and LIG3. Each is linked with ZNF774 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF774-to-partner and partner-to-ZNF774 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF774→partner) and Y-score (partner→ZNF774) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NAXE →	+0.363	+0.449	<.001	.001	3	5
HNSC	HNRNPR →	+0.320	+0.599	<.001	<.001	3	5
HNSC	LIG3 →	+0.491	+0.604	<.001	<.001	3	5
GBM	THEMIS2 →	-0.439	-0.433	<.001	.002	3	5
LSCC	PPP1R18 →	-0.432	-0.545	<.001	<.001	3	5
PDAC	DPY30 →	+0.548	+0.384	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,633 associations by consensus.

Exploration

ZNF774 survival (RNA) · tumor vs normal (RNA) · all ZNF774 data types