Across TCGA cell cohorts, ZNF774 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF774-associated genes across cancer lineages are MMP26 and OR2T29. Each is linked with ZNF774 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF774-to-partner and partner-to-ZNF774 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF774→partner) and Y-score (partner→ZNF774) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MMP26 →	+0.027	+3.217	.002	.006	3	1
LARGE_INTESTINE	OR2T29 →	+0.010	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

ZNF774 survival (RNA) · tumor vs normal (RNA) · all ZNF774 data types